I'd be more concerned about the disruption to the players regular week either side of the game, rather than the effects of a plastic pitch. Airport time, flying time, hotel stop-overs, 5 time zones both ways (jet lag) can all take their toll. This will eat into game prep, not just for the Toronto game, but also for the following week.
I know that football teams sometimes do this sort of thing. but they tend to have bigger squads.

Bonkers!